Biography

Professor Panoskaltsis is a clinician-scientist with a niche interest in translational interdisciplinary research and personalised therapeutics, focused in myeloid neoplasms. She completed her MD at the University of Toronto (Canada), clinical training and American Board Certification in Internal Medicine, Haematology and Bone Marrow Transplantation at the University of Rochester (USA) and a PhD in Immunology at Imperial College London (UK) where she remained as faculty until 2018. She has recently moved from Emory University and Georgia Institute of Technology (USA) and is now Professor in Personalised Therapeutics at Trinity College Dublin, Consultant Haematologist at St. James’s Hospital and an Adjunct Principal Investigator at NIBRT. She has an international reputation in cytokine release syndrome, in using bio-inspired three-dimensional (3D) ex vivo models to study normal and malignant hematopoiesis, and in creating novel precision immune-chemotherapeutics using mathematical modeling and ex vivo 3D perfusion bioreactor culture systems. She is a Fellow of the Royal College of Physicians (London), has received numerous awards for excellence in clinical care, research, entrepreneurship, and has several patents.

Research Interests

• Cytokine release syndrome

• Immune pathogenesis of acute myeloid leukemia

• Myeloid neoplasm biology

• Human hematopoietic organoids & 3D culture systems

• Personalised therapeutics

• In silico modeling of immuno-chemotherapy